Cancer Vaccines

Animal study identifies promising new target for brain tumor therapy

Published in Vaccine Weekly, May 23rd, 2007

A drug that targets the body’s immune cells may be effective in treating malignant brain tumors, according to a new study led by researchers from Duke’s Preston Robert Tisch Brain Tumor Center. In animal models, the drug re-engaged the body’s cancer-damaged immune system.

"We were effectively targeting ‘bad’ T cells that can damage the immune system if their numbers are too high, and ‘good’ T cells that help create an immune response to things like infections and tumors," said John Sampson, M.D., Ph.D., a neurosurgeon at Duke and senior investigator on the study. "We found that this drug was able to stop the bad cells in their tracks by giving the good ones a type of...

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Source: Vaccine Weekly (2007-05-23)

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