HIV/AIDS Vaccines
Research conducted at Children's Hospital has provided new information about HIV/AIDS vaccines
Published in Vaccine Weekly, May 30th, 2007
New research, "Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials," is the subject of a report. According to recent research from the United States, "Interferon-gamma (IFN-gamma) ELISpot and intracellular cytokine staining (ICS) assays are routinely employed in clinical HIV vaccine trials to identify antigen-specific T cells in cryopreserved peripheral blood mononuclear cells (PBMC). Several parameters involved in blood collection, processing and shipping may influence immunological function of the resulting cells, including anticoagulant type, time from venipuncture to PBMC isolation/cryopreservation, method of...
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Source: Vaccine Weekly (2007-05-30)
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