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HIV/AIDS Vaccines

New HIV/AIDS vaccines research from State Research Center of Virology and Biotechnology VECTOR outlined

Published in Vaccine Weekly, June 27th, 2007

A new study, "Combined virus-like particle-based polyepitope DNA/protein HIV-1 vaccine design, immunogenicity and toxicity studies," is now available. "We have previously described designing of polyepitope immunogens TBI and TCI, to stimulate the humoral and cellular immune responses to HIV-1. Here, immunogens TBI and TCI were used to create new vaccine construct named CombiHIVvac (Combined HIV-1 vaccine)," investigators in Russia report.

"CombiHIVvac is a virus-like particles (VLP) containing the DNA vaccine pcDNA-TCI as a core encapsulated within a spermidine-polyglucin-TBI conjugate. The immunogenic and toxic properties of the candidate vaccine CombiHIVvac have been...

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