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HIV/AIDS Vaccines

Studies from Uniformed Services University of the Health Sciences add new findings in the area of HIV/AIDS vaccines

Published in Vaccine Weekly, July 11th, 2007

Researchers detail in "Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunization," new data in HIV/AIDS. According to recent research from the United States, "An immunization regimen was evaluated in rabbits consisting of the soluble, oligomeric form of envelope glycoprotein of HIV-1, strain R2 (gp140(R2)), or the surface component of the same envelope (Env), gp120(R2), in the adjuvant AS02A. The gp140(R2) was selected based on its unusual CD4-independent phenotype and the exceptionally broad neutralizing response in the infected donor."

"The gp140(R2) immunogen induced antibodies that achieved 50% neutralization of 48/48, and 80%...

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