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Malaria Vaccines

Investigators at Seattle Biomedical Research Institute release new data on malaria vaccines

Published in Vaccine Weekly, July 18th, 2007

A new study, "Effects of sex, parity, and sequence variation on seroreactivity to candidate pregnancy malaria vaccine antigens," is now available. According to recent research from the United States, "Plasmodium falciparum-infected erythrocytes adhere to chondroitin sulfate A (CSA) to sequester in the human placenta, and pregnancy malaria (PM) is associated with the development of disease in and the death of both mother and child. A PM vaccine appears to be feasible, because women become protected as they develop antibodies against placental infected erythrocytes (IEs)."

"Two IE surface molecules, VAR1CSA and VAR2CSA, bind CSA in vitro and are potential vaccine...

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