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Immunization

Studies from Indian Institute of Science provide new data on immunization

Published in Vaccine Weekly, July 25th, 2007

A new study, "Immunization of mice with DNA coding for the variable regions of anti-idiotypic antibody generates antigen-specific response," is now available. According to a study from Bangalore, India, "Understanding the mechanisms of generation and maintenance of immunological memory is crucial for rational vaccine design. A hypothesis known as relay hypothesis was earlier proposed which explains the maintenance of immunological memory through interaction of idiotypic and anti-idiotypic lymphocytes."

"In the present study, we have shown that immunization with rinderpest virus hemagglutinin protein specific anti-idiotypic antibody (Ab(2)v(beta)) DNAs coding for heavy...

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