Cancer Vaccines
Scientists at Ohio State University publish research in cancer vaccines
Published in Vaccine Weekly, August 8th, 2007
Scientists discuss in "Peptide vaccines of the HER-2/neu dimerization loop are effective in inhibiting mammary tumor growth in vivo" new findings in cancer. "Human epidermal growth factor receptor-2 (HER-2)/neu (ErbB2), a member of the epidermal growth factor family of receptors, is overexpressed in 20-30% of breast cancers. It is an attractive target for receptor-directed antitumor therapy using mAbs," scientists writing in the Journal of Immunology report.
"Unlike other epidermal growth factor receptor family members, HER-2/neu does not bind a high-affinity ligand, but rather functions as the preferred dimerization partner. Pertuzumab (Omnitarg) is a humanized...
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Source: Vaccine Weekly (2007-08-08)
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