Cancer Gene Therapy
Studies from Ruhr University, Institute of Microbiology and Hygiene describe new findings in cancer gene therapy
Published in Vaccine Weekly, August 22nd, 2007
A report, "Intratumoral expression of respiratory syncytial virus fusion protein in combination with cytokines encoded by adenoviral vectors as in situ tumor vaccine for colorectal cancer," is newly published data in Molecular Cancer Therapeutics. "Although cancers can naturally elicit immune responses, immune ignorance is a common observation preventing immune-mediated elimination of tumor cells. We assessed whether intratumoral expression of respiratory syncytial virus fusion (RSV-F) protein, encoded by a replication-defective adenovirus vector (Ad.RSV-F), alone or in combination with local coexpression of cytokines can induce tumor-specific immune responses in a syngeneic murine...
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Source: Vaccine Weekly (2007-08-22)
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