Cancer Vaccines
Scientists at Gothenburg University detail research in cancer vaccines
Published in Vaccine Weekly, September 26th, 2007
Researchers detail in "Therapeutic dendritic cell vaccination with Ag coupled to cholera toxin in combination with intratumoural CpG injection leads to complete tumour eradication in mice bearing HPV 16 expressing tumours," new data in cancer. According to recent research from Gothenburg, Sweden, "We have evaluated whether cholera toxin (CT) can enhance the efficiency of therapeutic dendritic cell (DC) vaccination in mice bearing a human papilloma virus (HPV) 16 antigen (Ag) expressing tumour. Mice were therefore injected with the TC-1 cancer cell line expressing E6 and E7, which are the major oncogenic proteins produced in HPV-induced cervical cancer, and they were then vaccinated with Ag...
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Source: Vaccine Weekly (2007-09-26)
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