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HIV/AIDS Co-Infection Vaccines

Investigators at University of Alabama, Department of Medicine have published new data on HIV/AIDS co-infection vaccines

Published in Vaccine Weekly, October 31st, 2007

New investigation results, 'HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice,' are detailed in a study published in Vaccine. "'We have constructed a replication competent, gamma(1)34.5-deleted herpes simplex virus type-1 (HSV-1) vector (J200) that expresses the gag gene from human immunodeficiency virus type-1, primary isolate 89.6 (HIV-1(89.6)), as a candidate vaccine for HIV-1. J200 replicates in vitro, resulting in abundant Gag protein production and accumulation in the extracellular media," scientists in the United States report.

"Immunization of Balb/c mice with a single intraperitoneal...

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