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Peptide Vaccine

Findings from Hannover Medical School advance knowledge in peptide vaccine

Published in Vaccine Weekly, October 31st, 2007

Current study results from the report, 'Functional and phenotypic characterization of peptide-vaccine-induced HCV-specific CD8+ T cells in healthy individuals and chronic hepatitis C patients,' have been published. According to a study from Hannover, Germany, "'Only very limited information on phenotype and function of vaccine-induced CD8+ T cells is available for humans. We investigated hepatitis C virus-specific CD8+ T cells after vaccination with the HCV peptide-vaccine IC41 which includes 5 MHC-class I and 3 MHC class-II-restricted epitopes."

"In healthy subjects, IC41 induced both HCV-specific central memory as well as effector CD8+ T cells which rapidly expanded...

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