HIV/AIDS Co-Infection

New HIV vaccine target could solve mutation problem

Published in Vaccine Weekly, November 28th, 2007

Researchers at UCSF and the University of Toronto have identified a potential new way of fighting against HIV infection that relies on the remnants of ancient viruses, human endogenous retroviruses (HERV), which have become part of the genome of every human cell.

Mounting evidence suggests that HIV infection could enable HERV expression by disrupting the normal controls that keep HERV in check.

In some HIV-infected individuals, infection fighting T cells are able to target HERV expressing cells.

Researchers believe that their findings, published in the November 9, 2007 issue of the journal "PLoS Pathogens," could lead to a vaccine...

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Source: Vaccine Weekly (2007-11-28)

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