Smallpox Vaccines
New data from K.L. Karem et al illuminate research in smallpox vaccines
Published in Vaccine Weekly, January 23rd, 2008
According to recent research from the United States, "Following the U.S. monkeypox outbreak of 2003, blood specimens and clinical and epidemiologic data were collected from cases, defined by standard definition, and household contacts of cases to evaluate the role of preexisting (smallpox vaccine-derived) and acquired immunity in susceptibility to monkeypox disease and clinical outcomes. Orthopoxvirus-specific immunoglobulin G (IgG), IgM, CD4, CD8, and B-cell responses were measured at similar to 7 to 14 weeks and 1 year postexposure."
"Associations between immune responses, smallpox vaccination, and epiderniologic and clinical data were assessed. Participants were...
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Source: Vaccine Weekly (2008-01-23)
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