Gene Therapy

Scientists at University of Pittsburgh, Medical Department describe research in gene therapy

Published in Vaccine Weekly, January 23rd, 2008

"T-cell-mediated immunity is critical for the prevention and control of a broad range of infectious diseases and human malignancies. Genetic immunization is a promising approach for the elicitation of T-cell immunity," scientists in the United States report.

"Recombinant lentivectors are now being developed and evaluated as antigen delivery platforms for genetic immunization and immune engineering. Early results from studies utilizing lentivectors are promising. Third generation lentivectors have been engineered to improve biosafety and reduce antivector immune responses. The ability of third generation lentivectors to efficiently transduce non-dividing cells, including...

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Source: Vaccine Weekly (2008-01-23)

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