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Hepatitis C Virus

Reports from University of Sao Paulo add new data to research in hepatitis C virus

Published in Vaccine Weekly, January 23rd, 2008

"The ethnic influence makes it difficult to reach a consensual definition of host-dependent genetic factors controlling the hepatitis C virus (HCV) disease course. To investigate, in an ethnically complex Brazilian population, whether human leucocyte antigen (HLA) molecules are associated with susceptibility to HCV infection, self-limiting viral clearance and predisposition to chronic disease," investigators in Ribeirao Preto, Brazil report.

"One hundred and four HCV-antibody-positive patients (stratified into groups with spontaneous viral clearance and chronic HCV infection) and 166 healthy controls were submitted to HLA genotyping. Two strong associations were...

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