Immunization
Studies conducted at University of Auckland on immunization recently published
Published in Vaccine Weekly, February 13th, 2008
According to recent research published in the journal International Immunology, "We recently demonstrated that three antigen-presenting cell (APC) subsets exist in the healthy human dermis, CD14(+) and CD1a(+) dermal APCs and migratory dermal Langerhans cells. Here, we extend these findings by defining CD208 as an exclusive marker of migratory dermal Langerhans cells, confirming that migratory dermal Langerhans cells (CD1a(high) CD207(+) CD208(+)) and CD1a(+) dermal APCs (CD1a(mid) CD207(-) CD208(-)) are two distinct APC populations."
"Using flow cytometry and multicolor fluorescence immunohistochemistry, we demonstrated that there were striking differences...
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Source: Vaccine Weekly (2008-02-13)
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