Falciparum Malaria
New falciparum malaria research has been reported by scientists at Walter and Eliza Hall Institute of Medical Research
Published in Vaccine Weekly, February 13th, 2008
A new study, 'A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils,' is now available. "Merozoite surface protein 2 (MSP2) from the human malaria parasite Plasmodium falciparum is expressed as a GPI-anchored protein on the merozoite surface. It has been implicated in the process of erythrocyte invasion and is a leading vaccine candidate," researchers in Parkville, Australia report.
"MSP2 is an intrinsically unstructured protein (IUP), and recombinant MSP2 forms amyloid-like fibrils upon storage. We have examined synthetic peptides corresponding to sequences in the...
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Source: Vaccine Weekly (2008-02-13)
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