Cancer Vaccines

Data from R.J. Amato et al provide new insights into cancer vaccines

Published in Vaccine Weekly, February 20th, 2008

"Advanced renal cell carcinoma remains resistant to drug-, hormone-, and cytokine-based therapies. Promising new immunotherapeutic approaches include monoclonal antibodies, kinase inhibitors, mammalian target of rapamycin inhibition, dendritic cell, and tumor antigen vaccines," investigators in the United States report.

"Most of these approaches have yet to produce clinical responses significantly superior to those of previous standard therapies, although most are well tolerated and elicit relatively high rates of stable disease. Two recently approved agents, a kinase inhibitor and a mTOR inhibitor, are recommended for use as first-line therapies against renal cell...

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Source: Vaccine Weekly (2008-02-20)

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