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Vaccine Weekly

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Hepatitis A Virus Vaccines



Research from Health Protection Agency Center for Infections reveals new findings on hepatitis A virus vaccines



March 12th, 2008

Data detailed in 'Protecting contacts of hepatitis A: what's the difference between vaccine and human normal immunoglobulin' have been presented. According to recent research from London, the United Kingdom, "The efficacy of vaccine when time since exposure is prolonged (more than 1 week from onset of illness in the index case) is unknown, but is likely to be significantly lower than human normal immunoglobulin (HNIG). We estimated the number of additional secondary cases that may occur through giving vaccine instead of HNIG to contacts of cases of hepatitis A who are identified more than 1 week after onset in the index case."

"This was calculated for different levels...


Source: Vaccine Weekly (2008-03-12)

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