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Influenza Vaccines



Researchers from University of Washington, Benaroya Research Institute at Virginia Mason detail findings in influenza vaccines



March 12th, 2008

New research, 'Healthy human subjects have CD4+ T cells directed against H5N1 influenza virus,' is the subject of a report. According to a study from the United States, "It is commonly perceived that the human immune system is naive to the newly emerged H5N1 virus. In contrast, most adults have been exposed to influenza A H1N1 and H3N2 viruses through vaccination or infection."

"Adults born before 1968 have likely been exposed to H2N2 viruses. We hypothesized that CD4(+) T cells generated in response to H1N1, H3N2, and H2N2 influenza A viruses also recognize H5N1 epitopes. Tetramer-guided epitope mapping and Ag-specific class II tetramers were used to identify...


Source: Vaccine Weekly (2008-03-12)

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