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Allergies
Recent studies by J. Gluck and co-authors add new data to allergies findings
March 12th, 2008
According to a study from Zabrze, Poland, "T helper subset dysregulation is evident in allergic disorders. The role of T cytotoxic subsets is less understood." "We investigated whether allergen immunotherapy in intermittent allergic rhinitis influences the intracellular expression of IL-4 and IFN-gamma by CD3(+)CD8(-) and CD3(+)CD8(+) cells. Nineteen adult patients with intermittent allergic rhinitis were evaluated before the pollen season, and then after one preseasonal course of subcutaneous allergen immunotherapy. Twelve healthy nonatopic patients matched for age and sex served as controls. Intracellular expression of IFN-gamma and IL-4 by CD3(+)CD8(-) (Th1 and Th2,...
Source: Vaccine Weekly (2008-03-12)
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