Cancer Vaccines

Reports from Pohang University of Science and Technology describe recent advances in cancer vaccines

Published in Vaccine Weekly, March 12th, 2008

According to recent research from South Korea, "Microvesicles (MV) are membrane vesicles secreted from the plasma and endosomal membrane compartment by various cell types such as hematopoietic, epithelial, and tumor cells. Actively growing tumor cells shed MV, and the rate of shedding increases in malignant tumors."

"Although recent progress in this area has revealed that tumor-derived MV play multiple roles in tumor growth and metastasis via immune escape, tumor invasion, and angiogenesis, the mechanism of vesicle formation and the biological roles of tumor-derived MV are not understood. Here, we report the first global proteomic analysis of highly purified MV from...

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Source: Vaccine Weekly (2008-03-12)

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