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Vaccine Weekly

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HIV/AIDS



New research on HIV/AIDS from B.S. Andresen and co-authors summarized



March 12th, 2008

According to recent research published in the journal AIDS Research and Human Retroviruses, "We report here the near full-length sequence characterization of 17 Danish clinical HIV-1 strains isolated from HLA-A02 patients not in need of ART, with relatively low viral loads and normal CD4 cell counts. Sequencing was performed directly on DNA extracted from short-term cocultures of PBMCs."

"The near full-length genomes did not contain any major insertions, deletions, or rearrangements. Sixteen of the isolates were characterized as nonrecombinant subtype B and one isolate as nonrecombinant subtype C. Phylogenetic analysis did not reveal any founder effect among the...


Source: Vaccine Weekly (2008-03-12)

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