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HIV/AIDS



Researchers from Montana State University publish new studies and findings in the area of HIV/AIDS



March 12th, 2008

According to a study from the United States, "Monoclonal antibodies specific for the conserved CD4 binding site region of the HIV envelope protein gp120 were used to select phage from two different random peptide display libraries. Synthetic peptides were made with sequences corresponding to those displayed on the selected phage, and peptide-protein fusions were expressed that contained the selected phage-displayed peptide sequence and either the N-terminal domain of the phage pIII protein or the small heat shock protein of Methanococcus jannaschii or both."

"For monoclonal antibody 5145A, these constructs containing the selected peptide sequences were all capable of...


Source: Vaccine Weekly (2008-03-12)

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