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Vaccine Weekly

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Tetanus



New tetanus research from University of Nice outlined



March 12th, 2008

According to a study from Nice, France, "Although often requiring the development of efficient adjuvants, needle-free mucosal delivery of vaccine is of major interest as a strategy of mass immunization against infectious diseases."

"We report that mucosal immunization against tetanus toxoid through nasal route, together with active cytotoxic necrotizing factor 1 (CNF1), elicits a specific and long lasting anti-tetanus toxin response, comprising seric IgG and IgA, as well as mucosal IgA. Immunized mice were protected against a challenge with lethal doses of tetanus toxin (10 x LD50)," wrote P. Munro and colleagues, University of Nice.

The researchers...


Source: Vaccine Weekly (2008-03-12)

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