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Encephalomyelitis Immunology
Reports outline encephalomyelitis immunology study results from N.A. Pfender et al
March 12th, 2008
New research, 'Route of uptake of palmitoylated encephalitogenic peptides of myelin proteolipid protein by antigen-presenting cells: importance of the type of bond between lipid chain and peptide and relevance to autoimmunity,' is the subject of a report. According to recent research from Strasbourg, France, "Previously, we have shown that thiopalmitoylation of peptides of myelin proteolipid protein, as occurs naturally in vivo, increases their ability to induce experimental autoimmune encephalomyelitis, the animal model of multiple sclerosis, and skews the autoimmune response toward a CD4(+)-mediated response. In contrast, the same peptide, when synthesized with a stable amide bond...
Source: Vaccine Weekly (2008-03-12)
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