Vaccine Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Vaccine Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Glioblastoma Genetics
Data on glioblastoma genetics reported by researchers at University of California
March 12th, 2008
Fresh data on glioblastoma are presented in the report 'Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples.' "Epidermal growth factor receptor variant III (EGFRvIII) is an oncogenic, constitutively active mutant form of the EGFR that is commonly expressed in glioblastoma and is also detected in a number of epithelial cancers. EGFRvIII presents a unique antigenic target for anti-EGFRvIII vaccines and it has been shown to modulate response to EGFR kinase inhibitor therapy," researchers in the United States report. "Thus, detection in clinical samples may be warranted. Existing patents preclude the use of anti-EGFRvIII antibodies for...
Source: Vaccine Weekly (2008-03-12)
|
