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Vaccine Weekly

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Metaplasia Vaccines



Researchers' work from Instituto Politecnico Nacional focuses on metaplasia vaccines



March 12th, 2008

New investigation results, 'Intranasal immunization with Naegleria fowleri lysates and Cry1Ac induces metaplasia in the olfactory epithelium and increases IgA secretion,' are detailed in a study published in Parasite Immunology. According to recent research published in the journal Parasite Immunology, "According to previous reports, intranasal administration of the Cry1Ac protein alone or with amoebic lysates increases protection against Naegleria fowleri meningoencephalitis in mice, apparently by eliciting IgA responses in the nasal mucosa. In the current study, we performed an immunohistochemical analysis of IgA in the nasal mucosa of mice immunized intranasally with...


Source: Vaccine Weekly (2008-03-12)

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