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Vaccine Weekly

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Polio Vaccines



Research on polio vaccines reported by scientists at Centers for Disease Control and Prevention



March 12th, 2008

Researchers detail in 'Failure to detect infection by oral polio vaccine virus following natural exposure among inactivated polio vaccine recipients,' new data in polio. According to a study from the United States, "While oral polio vaccine (OPV) has been shown to be safe and effective, it has been observed that it can circulate within a susceptible population and revert to a virulent form. Inactivated polio vaccine (IPV) confers protection from paralytic disease, but provides limited protection against infection."

"It is possible, then, that an IPV-immunized population, when exposed to OPV, could sustain undetected circulation of vaccine-derived poliovirus. This study...


Source: Vaccine Weekly (2008-03-12)

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