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Vaccines
Data on vaccines described by researchers at Stallergenes SA
March 12th, 2008
According to recent research from Antony, France, "In this study, we tested two triacylated pseudo-dipeptidic molecules, OM-197-MP-AC and OM-294-BA-MP as candidate adjuvants for allergy vaccines. Both molecules induce human dendritic cell (h-DC) maturation and polarize naive T cells toward the Th1 type with IFN-gamma production." "Only OM-294-BA-MP induces IL10 gene expression both in monocyte- derived DCs and CD4+ naive T cells. Sublingual administration of OM-294-BA-MP plus the antigen enhances tolerance induction in BALB/c mice with established asthma to ovalbumin with an impact on both airways hyperresponsiveness and lung inflammation," wrote L. Mascarell and...
Source: Vaccine Weekly (2008-03-12)
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