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Gene Therapy
Reports from Imperial College London, Department of Immunology highlight recent research in gene therapy
March 19th, 2008
Current study results from the report, 'Activity of different vaccine-associated promoter elements in human dendritic cells,' have been published. According to recent research from London, the United Kingdom, "Vaccine design approaches that target dendritic cells (DC) aim at achieving high levels of transgene expression. Careful selection of the promoter element driving the foreign gene is therefore important." "We have constructed adenovirus vectors carrying the gene for enhanced green fluorescent protein (eGFP) driven by three different promoters, CMV, CMV5 and ubiquitin C (UbC) promoter, and analysed their activity in different populations of human DC, namely blood...
Source: Vaccine Weekly (2008-03-19)
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