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Hepatitis B Virus Vaccines
Studies from Federal University of Minas Gerais, Institute for Biological Science provide new data on hepatitis B virus vaccines
March 19th, 2008
A new study, 'Protective immunization against murine cytomegalovirus infection using adenoviruses and poxviruses expressing hepatitis B virus chimeras,' is now available. According to a study from Belo Horizonte, Brazil, "Recombinant adenoviruses, poxviruses, and plasmid DNA vaccines encoding different hepatitis B virus (HBV)/murine cytomegalovirus (MCMV) protein chimeras were used to immunize mice. Processing of the chimeras resulted in presentation of a protective Ld/CD8+ T-cell epitope of the immediate early 1 protein pp89 (IE1 pp89) of MCMV to the immune system." "Different levels of immunogenicity were observed depending on: (i) the type of viral vector used, (ii)...
Source: Vaccine Weekly (2008-03-19)
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