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Influenza Vaccines
Recent findings from S. Deroo and co-authors highlight research in influenza vaccines
March 19th, 2008
New investigation results, 'Non-immunized natural human heavy chain CDR3 repertoires allow the isolation of high affinity peptides mimicking a human influenza hemagglutinin epitope,' are detailed in a study published in Molecular Immunology. "In this study we constructed two phage libraries displaying non-immunized natural human IgM derived HCDR3 repertoires. One library was structurally constrained by a Gly to Cys substitution at position 104 enabling the formation of a disulfide bridge with the Cys at position 92," investigators in Luxembourg report. "Panning of these libraries on an anti-human influenza hemagglutinin (HA) antibody resulted in the selection of...
Source: Vaccine Weekly (2008-03-19)
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