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Vaccine Weekly

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Influenza Vaccines



Research reports from Yonsei University, Department of Biotechnology provide new insights into influenza vaccines



March 19th, 2008

Research findings, 'Development and characterization of a live attenuated influenza B virus vaccine candidate,' are discussed in a new report. According to recent research from Seoul, South Korea, "A human influenza B/Lee/40 virus was cold-adapted by serial passages in embryonated chicken eggs, at progressively lower temperatures, for possible use as a future influenza B vaccine donor strain. Temperature sensitive and cold-adapted phenotypes were achieved as a consequence of the adaptation process."

"It was determined that the virus was attenuated in mice since the replication of the viral genome was significantly reduced in the lung. Despite decreased viral...


Source: Vaccine Weekly (2008-03-19)

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