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Cancer Vaccines
USC researchers discover novel way to develop tumor vaccines
March 19th, 2008
Researchers at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells. The results of the study, titled "A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression," will be published in Nature Medicine on March 2, 2008. "Under normal circumstances, regulatory T cells inhibit the immune system to attack its own cells and tissues to prevent autoimmune diseases. Cancer cells take advantage of regulatory T cells' suppressor ability, recruiting them to keep the immune system at bay or disabling the immune...
Source: Vaccine Weekly (2008-03-19)
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