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Cancer Vaccines
Findings from D.M. Prowse and co-authors provide new insights into cancer vaccines
March 19th, 2008
According to a study from London, the United Kingdom, " Human papillomaviruses (HPVs) are sexually transmitted human carcinogens that may play a role in the oncogenesis of penile cancer. Objectives To investigate the role of HPV infection and expression of the tumour suppressor protein p16(INK4A) in the pathogenesis of penile cancer." " By means of polymerase chain reaction amplification and reverse hybridization line probe assay to detect HPV infection, and immunohistochemical staining for p16(INK4A) and Ki67, we analysed 26 penile squamous cell carcinomas (SCCs) and 20 independent penile lichen sclerosus (LS) lesions from 46 patients. HPV DNA was found in 54% of...
Source: Vaccine Weekly (2008-03-19)
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