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Vaccine Weekly

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Histoplasmosis



Reports outline histoplasmosis study findings from P.A. Connolly and colleagues



March 19th, 2008

"The second-generation Histoplasma antigen immunoassay is semiquantitative, expressing results as a comparison to a negative control, which requires repeat testing of the prior specimen with the current specimen to accurately determine a change in antigen. Reporting results in this manner often is confusing to the ordering physician and laboratory," researchers in the United States report.

"Development of a quantitative assay could improve accuracy, reduce interassay variability, and eliminate the need to test the prior sample with the current sample in the same assay. Calibrators with known concentrations of Histoplasma antigen were used to quantitate antigen in...


Source: Vaccine Weekly (2008-03-19)

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