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Cancer Vaccines
Research on cancer vaccines described by scientists at University of California, Department of Medicine
March 19th, 2008
New research, 'Dendritic cells loaded with apoptotic antibody-coated tumor cells provide protective immunity against B-cell lymphoma in vivo,' is the subject of a report. "The in vitro priming of tumor-specific T cells by dendritic cells (DCs) phagocytosing killed tumor cells can be augmented in the presence of antitumor monoclonal antibody (mAb). We investigated whether DCs phagocytosing killed lymphoma cells coated with tumor-specific antibody could elicit antitumor immunity in vivo," researchers in the United States report. "Irradiated murine 38C13 lymphoma cells were cocultured with bone marrow-derived DCs in the presence or absence of tumor-specific mAb. Mice...
Source: Vaccine Weekly (2008-03-19)
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