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Vaccine Weekly

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Vaccines



New vaccines study findings have been reported by S. Okamoto and co-researchers



March 26th, 2008

"Japanese encephalitis (JE) is a serious disease caused by the JE virus (JEV), and vaccination is the only way to prevent the diseases. In Japan, the only JE vaccine currently available is an inactivated vaccine that requires multiple doses for effective protection; therefore, an effective single-dose vaccine is needed," scientists in Osaka, Japan report.

"However, no report of an effective protocol for a single dose of JE vaccine in animals has been published. Here, we evaluated the efficacy of a single-close vaccination in mice to which the JE vaccine was given with or without adjuvant. Biodegradable poly(gamma-glutamic acid) nanopartictes (gamma-PGA-NPs) were used as...


Source: Vaccine Weekly (2008-03-26)

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