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Chlamydia Vaccines
New chlamydia vaccines findings from British Columbia Center for Disease Control published
March 26th, 2008
New research, 'Immunoproteomic discovery of novel T cell antigens from the obligate intracellular pathogen Chlamydia,' is the subject of a report. "Chlamydia infections cause substantial morbidity worldwide and effective prevention will depend on a vaccine. Since Chlamydia immunity is T cell-mediated, a major impediment to developing a molecular vaccine has been the difficulty in identifying relevant T cell Ags," scientists in Vancouver, Canada report. "In this study, we used a combination of affinity chromatography and tandem mass spectrometry to identify 13 Chlamydia peptides among 331 self-peptides presented by MHC class II (I-A(b)) molecules from bone marrow-derived...
Source: Vaccine Weekly (2008-03-26)
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