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Vaccine Weekly

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Immunology



New immunology study findings have been published by scientists at University of Pennsylvania, Department of Microbiology



March 26th, 2008

New research, 'Novel vaccination protocol with two live mucosal vectors elicits strong cell-mediated immunity in the vagina and protects against vaginal virus challenge,' is the subject of a report. According to recent research from the United States, "Most HIV infections result from heterosexual transmission to women. Because cellular immunity plays a key role in the control of the infection, we sought to strengthen cellular immune responses in vaginal tissue."

"We explored a novel prime-boost protocol that used two live mucosal agents that trigger different pathways of innate immunity and induce strong cellular immunity. Adenovirus serotype 5 (Ad5) has frequently been...


Source: Vaccine Weekly (2008-03-26)

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