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Vaccine Weekly

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Influenza Immunology



Research from Duke University, Human Vaccine Institute reveals new findings on influenza immunology



March 26th, 2008

New research, 'CCR2+ monocyte-derived dendritic cells and exudate macrophages produce influenza-induced pulmonary immune pathology and mortality,' is the subject of a report. According to recent research published in the Journal of Immunology, "Infection with pathogenic influenza virus induces severe pulmonary immune pathology, but the specific cell types that cause this have not been determined. We characterized inflammatory cell types in mice that overexpress MCP-1 (CCL2) in the lungs, then examined those cells during influenza infection of wild-type (WT) mice."

"Lungs of both naive surfactant protein C-MCP mice and influenza-infected WT mice contain increased...


Source: Vaccine Weekly (2008-03-26)

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