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Vaccine Weekly

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Vaccines



Research conducted at Churchill Hospital has provided new information about vaccines



March 26th, 2008

Data detailed in 'The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response' have been presented. According to recent research published in the Journal of Immunology, "Rapid waning of anti-polysaccharide bactericidal Ab and vaccine effectiveness is observed following infant immunization with the serogroup C meningococcal (MenC) glycoconjugate vaccine. This is despite the demonstrable presence of immunological memory."

"Persistence of functional Ab, therefore, appears to be the key determinant of MenC...


Source: Vaccine Weekly (2008-03-26)

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