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DNA Vaccines
New DNA vaccines research has been reported by J. Xiao et al
April 9th, 2008
According to recent research from Beijing, People's Republic of China, "Collagen-induced arthritis (CIA) is an animal model, which closely resembles human rheumatoid arthritis (RA) in pathogenesis and pathology. Evidence suggests that the inhibition of T lymphocytes or their functions can alleviate the progression of arthritis." "So the administration of arthritogenic T cell receptor (TCR) variable region peptide or DNA vaccines encoding pathogenic TCR V beta variable region may provide useful information for designing specific immunotherapies against autoimmune diseases. Heat shock proteins (HSPs) have the function of raising antigenic immunogenicity and HSP70 has a...
Source: Vaccine Weekly (2008-04-09)
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