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Vaccine Weekly

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HIV/AIDS



New HIV/AIDS data have been reported by A. Drogoz and co-authors



April 9th, 2008

"This work reports on the interactions of a model protein (p24, the capside protein of HIV-1 virus) with colloids obtained from polyelectrolyte complexes (PECs) involving two polysaccharides: chitosan and dextran sulfate (DS). The PECs were elaborated by a one-shot addition of default amounts of one counterpart to the polymer in excess," scientists in Lyon, France report.

"Depending on the nature of the excess poly electrolyte, the submicrometric colloid was either positively or negatively charged. HIV-1 capsid p24 protein was chosen as antigen, the ultrapure form, lipopolysaccharide-free (endotoxin-, vaccine grade) was used in most experiments, as the level of purity...


Source: Vaccine Weekly (2008-04-09)

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