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Malaria Vaccines
New research on malaria vaccines from S. Pichyangkul and co-authors summarized
April 9th, 2008
"Several lines of evidence suggest that targeting pre-erythrocytic-stage parasites for malaria vaccine development can provide sterile immunity. The objectives of this study were (i) to evaluate preclinically the safety and immunogenicity of a new recombinant pre-erythrocytic-stage antigen, liver-stage antigen 1 (LSA1), in nonhuman primates; and (ii) to investigate the potential for immune interference between LSA1 and the leading malaria vaccine candidate, RTS,S, by comparing the immune responses after single-antigen vaccination to responses after simultaneous administration of both antigens at separate sites," investigators in Bangkok, Thailand report. "Using a rhesus...
Source: Vaccine Weekly (2008-04-09)
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