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Whooping Cough
Findings from M. Hijnen et al in whooping cough reported
April 9th, 2008
According to recent research from Bilthoven, Netherlands, "Although vaccines against Bordetella pertussis, the causative agent of whooping cough, have been in use for over 50 y, the disease has remained endemic and is still a public health problem in many countries. It has been shown that antibody titres against pertactin, which is 1 of the exposed virulence factors of pertussis, correlate with protection and pertactin is now 1 of the components of most acellular pertussis vaccines." "However, little is known about the structure and location of protective epitopes on pertactin. Here we set out to investigate the antibody response using naturally occurring pertactin...
Source: Vaccine Weekly (2008-04-09)
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