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Vaccine Weekly

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Cancer Vaccines



Research on cancer vaccines published by scientists at University of Pennsylvania, Microbiology Department



April 9th, 2008

Fresh data on cancer are presented in the report 'Listeriolysin O is an improved protein carrier for lymphoma immunoglobulin idiotype and provides systemic protection against 38C13 lymphoma.' According to a study from the United States, "Follicular lymphoma (FL) is a disease that responds to current treatment regimens; however, patients in general relapse with increasingly refractory disease. Idiotype-based vaccines are currently under trial for the treatment of FL."

"These vaccines comprise the patient's BCR idiotype (Id) as the tumor antigen conjugated to the protein carrier Keyhole Limpet Hemocyanin (KLH); however, other protein carriers may enhance the immune...


Source: Vaccine Weekly (2008-04-09)

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