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Cancer Vaccines Immunology
Research from Ludwig Institute for Cancer Research in cancer vaccines immunology provides new insights
April 9th, 2008
A new study, 'Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production,' is now available. According to recent research from Heidelberg, Australia, "Activin-A is a transforming growth factor-beta (TGF-beta) superfamily member that plays a pivotal role in many developmental and reproductive processes. It is also involved in neuroprotection, apoptosis of tumor and some immune cells, wound healing, and cancer." "Its role as an immune-regulating protein has not previously been described. Here we demonstrate for the first time that activin-A has potent autocrine effects on the capacity of human...
Source: Vaccine Weekly (2008-04-09)
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