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Vaccine Weekly

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Falciparum Malaria Vaccines



Studies from Biotechnology Research Center further understanding of falciparum malaria vaccines



April 9th, 2008

Current study results from the report, 'Plasmodium falciparum: sequence analysis of the gene encoding the C-terminus region of the merozoite surface protein-1, a potential malaria vaccine antigen, in Iranian clinical isolates,' have been published. "C-terminal region of merozoite surface protein-1 of Plasmodium falciparum (PfMSP-1) isolated from different parts of the world revealed sequence variability, however no data exist on sequence heterogeneity of this region from Iran. To address this question, DNA encoding the carboxyl (C)-terminal region of PfMSP-1 was amplified in 144 Iranian P. falciparum clinical isolates, using allele type-specific primers," scientists writing...


Source: Vaccine Weekly (2008-04-09)

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